Author: jezzabellemente

SHANGHAI, Apr. 2, 2021 /Xinhua-AsiaNet/–

On March 31, 2021, Jemincare Group announced that their anti-SARS-CoV-2 neutralizing antibody, JMB2002, independently developed by Jemincare Shanghai Research Center, was approved by FDA for clinical trial in the United States.

Preclinical data showed that JMB2002 can precisely occupy the key epitope of the receptor binding domain (RBD) on the S1 subunit of the SARS-CoV-2 with human angiotensin-converting enzyme II (hACE2) binding interface, and has strong binding and blocking activities to the spike glycoproteins of mutant viruses including the South African mutant (B.1.351), the UK mutant (B.1.1.7) and the Brazilian mutant (P.1) .

In February of this year, Jemincare researchers published on bioRxiv website a paper entitled “A human antibody with blocking activity to RBD proteins of multiple SARS-CoV-2 variants including B.1.351 showed potent prophylactic and therapeutic efficacy against SARS-CoV-2 in rhesus macaques”. The preprint paper reported that JMB2002 showed 6.8-fold and 1.9-fold higher binding affinity to SARS-CoV-2 S1 mutant proteins of South African mutant and UK mutant respectively in comparison to that of prototype S1, indicating that JMB2002 would likely keep the neutralize potency against the South Africa and UK mutants. In the latest lab study, JMB2002 also showed 7-fold higher affinity to S1 RBD of Brazilian variant compared to prototype S1 RBD, suggesting that JMB2002 would also likely retain the neutralize potency against the Brazilian variant.

In the middle of January, 2021, Jemincare has initiated the phase I clinical trial of Chinese healthy subjects. Dosing of all cohorts is completed in the phase I clinical trial in China. Now, JMB2002 was approved by FDA for clinical trial in US, that would add an option for prophylactic and therapeutic intervention of SARS-CoV-2 utilizing JMB2002 to slow down the transmission of currently emerged SARS-CoV-2 variants and that would likely result in more efficient control of the COVID-19 pandemic.

As one of the top pharmaceutical groups in China, Jemincare Group, has focused on the R&D of new drugs with pipeline for treating diseases in cancer, central nervous system, respiratory system, cardiovascular and cerebrovascular systems. Jemincare has established its Research Center in Shanghai Zhangjiang Science City and has recruited over 400 R&D scientists for development of innovative drugs including biologics, novel small molecules, novel drug delivery system, generic drugs and traditional Chinese medicines.

For more information, please visit: http://www.jemincare.com/, or contact:
PR@jemincare.com

Source: Jemincare 

HONG KONG, March 31 (Bernama-BUSINESS WIRE) — Hong Kong leads the Asia’s 50 Best Restaurants 2021 list with 11 entries and The Chairman becoming the first Hong Kong restaurant to win top spot. Launched in 2009, the Cantonese restaurant in Central is renowned for its authentic, ingredients-driven cuisine. It won both coveted titles – The Best Restaurant in Asia and The Best Restaurant in China.

This press release features multimedia. View the full release here: 
https://www.businesswire.com/news/home/20210325006003/en/

Held virtually before a global audience on 25 March, the Asia’s 50 Best Restaurants 2021 awards ceremony also announced other Hong Kong restaurants that made the list, including newcomer Mono (No.44), as well as re-entries Caprice (No.28) and Ta Vie (No.38). Vea (No.16) doubled as this year’s recipient of the Gin Mare Art of Hospitality Award.

“This announcement marks a fruitful year for Hong Kong’s thriving dining scene, reflecting the rich diversity of local and international cuisines and admirable trove of culinary talent in the city,” said Mr Dane Cheng, Executive Director of the Hong Kong Tourism Board (HKTB).

“It takes both passion and a strong, progressive entrepreneurial spirit to succeed in Hong Kong’s competitive restaurant industry. So my heartfelt congratulations to all the winning restaurants and sincere appreciation for all the effort they have put into making Hong Kong one of the world’s top food destinations.”

Hong Kong is also represented by Neighborhood (No.17), Belon (No.25), 8½ Otto e Mezzo Bombana (No.33), Amber (No.37), Lung King Heen (No.47) and Seventh Son (No.48).

For the full list, please visit www.theworlds50best.com/asia/en/list/1-50.

View source version on businesswire.com: 
https://www.businesswire.com/news/home/20210325006003/en/

Contact

For media enquiries:

Ms Vivian Li
Email: vivian.li@hktb.com

Source : Hong Kong Tourism Board

–BERNAMA

Leading university pioneers use of graph analytics with AI, machine learning and translational bioinformatics to better predict treatment outcomes

REDWOOD CITY, Calif., March 30 (Bernama-GLOBE NEWSWIRE) —TigerGraph, provider of the leading graph analytics platform, today announced that the Technical University of Denmark (DTU), a leading university in the areas of technical and natural sciences, is using TigerGraph’s advanced graph analytics with machine learning and AI techniques to improve the treatment of acute lymphoblastic leukemia.

Researchers at DTU are part of a major project across Denmark and Sweden to map genetic material for everyone with childhood cancer. As part of a larger collaboration through the EU-funded iCOPE (Interregional Childhood Oncology Precision Medicine Exploration), the process starts with patient blood tests that through Whole Genome Sequencing (WGS) paired with RNA-seq expression data are used to find aberrant expression patterns correlated or possibly caused by enhancer mutations. The long term goal of iCOPE is to improve diagnostics, treatment, cure rates, and the overall life situation of children with cancer.

This process generates enormous amounts of data that using TigerGraph will be linked together with various other data points about the patient’s life, illness, and treatment in order to understand to a much greater extent why children get cancer, provide earlier diagnosis and far more effective treatment.

As Jesper Vang, PhD Student, Department of Health Technology, Cancer Systems Biology at DTU, explains, “Our current system only hosts raw data such as genotype and whole-genome sequenced data. This raw data is run through a custom pipeline that calls genetic variants and annotates the data in a MySQL DB. However, we needed something easier to work with specifically for the clinical personnel, that also allows them to look up genetic associations which is a perfect use case for graph analytics.”

DTU opted for an on-premise graph database platform that would deliver the required performance and evaluated a number of options, in particular, Neo4j, but concluded that only TigerGraph could scale and provide the analytical depth the project required. “In our testing, TigerGraph was the only solution offering the highest performance with the ability to scale to the levels we will eventually need,” explains Vang.

DTU is in the final stages of bringing the full system online and it is already being used in a specific project that combines the fields of AI, machine learning and translational bioinformatics to create models that can predict the risk of relapse and toxicity within acute lymphoblastic leukemia treatments.

Martin Darling, VP EMEA at TigerGraph, added, “The work at DTU and across the wider iCOPE project is transformational and highlights how the application of clinical excellence with innovative technologies can unlock breakthrough insights within areas such as life sciences. We are delighted to have Jesper present a full case study on the project at the upcoming Graph + AI Summit this April.”

TigerGraph’s upcoming Graph + AI Summit, the industry’s only open conference for accelerating analytics, AI, and machine learning with graph, will feature customer use case sessions and speakers from the world’s largest companies and most innovative startups and universities. Keynote speakers include Harry Powell, director of data and analytics at Jaguar Land Rover, who will share how Jaguar Land Rover used graph to accelerate supply chain planning from three weeks to 45 minutes and deliver three times the business value from data. Noel Yuhanna, Vice President and Principal Analyst at Forrester Research, will bring insights from Forrester clients across all industries who are driving business outcomes by combining graph-based analytics, AI, and machine learning. Danny Clark, Head of Fraud Strategy at NewDay, will explain how they identify and prevent fraudsters from joining their network faster than ever before by using graph and machine learning to check data against known and new fraud syndicates. Graph + AI Summit, the industry’s only open conference for accelerating analytics and AI, will run as a virtual conference on April 21-22, 2021. To register for the event, please visit https://www.tigergraph.com/graphaisummit/.

About the Technical University of Denmark (DTU)
DTU was founded in 1829 and has ever since been dedicated to developing the natural and the technical sciences with a view to creating value for society. During the past two centuries, DTU has undergone a transformation from a 19th-century polytechnical institution to a present-day international, multidisciplinary institution that caters for research, teaching, and collaboration across scientific, professional, and geographical borders.

Helpful Links

· Graph + AI Summit
· Get TigerGraph
· TigerGraph Cloud
· TigerGraph Website
· TigerGraph Blog
· TigerGraph on Twitter
· TigerGraph on LinkedIn

About TigerGraph  
TigerGraph is a platform for advanced analytics and machine learning on connected data. Based on the industry’s first and only distributed native graph database, TigerGraph’s proven technology supports advanced analytics and machine learning applications such as fraud detection, anti-money laundering (AML), entity resolution, customer 360, recommendations, knowledge graph, cybersecurity, supply chain, IoT, and network analysis. The company is headquartered in Redwood City, California, USA. Start free with tigergraph.com/cloud.

Media Contact

Cathy Wright

Offleash PR for TigerGraph

cathy@offleashpr.com

650-678-1905

SOURCE: TigerGraph, Inc.

–BERNAMA

KUALA LUMPUR, March 26 — The six-month Public Selection for outstanding young talents in China’s Wuxi comes to the final competition tomorrow.

According to the Wuxi Municipal People’s Government in a statement, although less than 1/30 of the contestants got selected, the organisers embraced more with the greatest enthusiasm with the rest of contestants.

‘Let the hearts of talents stay in Wuxi’, a related person from the organisation said.

This year, more than 10,000 qualified young talents participated in the competition.

Through the preliminary assessment, nearly 1,000 people came to Wuxi for the final competition, and only 270 people eventually became ‘selected talents’.

But even if not selected, after the evaluation, the local organiser invited 88 Wuxi-owned enterprises, institutions, and leading enterprises to provide 1,359 positions, which are generally well paid.

The Wuxi epidemic prevention and isolation point also set up a test centre for participants returning from overseas and still in the isolation period having a fair chance to compete.

In addition, young talents who cannot come to the scene can also run for suitable positions through online channels.

This public selection activity lasted for three years. The number of places has risen from 40 to 280 last year, and 270 this year.

Wuxi has been advocating culture and education since ancient times. Talents will be intensively cultivated in their careers in Wuxi. More importantly, the locals will create a sense of belonging like home for young talents globally.

The 2022 Public Selection will start in the second half this year.

— BERNAMA

KUALA LUMPUR, March 29 (Bernama) — The Chiba Prefectural Government has completed a new fight song, ‘CHI-BA Mystery Expedition!’ for the prefecture’s mascot named CHI-BA+KUN.

The song was produced by ‘Charat’, a musical unit which composes, sings, and choreographs theme songs for regional characters throughout Japan.

The lyrics and choreography, which incorporate an upbeat tempo, cheerful and trendy melody, with characteristics of CHI-BA+KUN and charms of Chiba Prefecture, are nicely combined, projecting CHI-BA+KUN’s cheerful and energetic image.

According to a statement, the song is scheduled to be performed at various places.

CHI-BA+KUN is a curious creature born and living in Chiba Prefecture. Full of curiosity, he loves to challenge everything. When he ventures into the unknown, courage and passion spring afresh, making his body glow with red.

The mascot’s side profile represents the shape of Chiba Prefecture.

Watch the video at https://www.youtube.com/watch?v=ug32ROQJa8k

— BERNAMA