CONAGEN STARTS FIRST COMMERCIAL PRODUCTION OF SUSTAINABLE TYRIAN PURPLE FOR TEXTILE DYE

New era for green tech alternatives to replace petrochemical synthesized dyes.

Bedford, Mass., Jan 10 (Bernama-GLOBE NEWSWIRE) — Conagen announced the successful scale-up of its sustainable, cost-effective Tyrian purple, a historically coveted and expensive dye found in rare and limited sources in marine nature.

Conagen is the world’s first and only biotechnology company commercializing a sustainable Tyrian purple by fermentation. As with any biologically-sourced textile dye, this color-fast compound reduces pollution and carbon footprints when used as an alternative to petrochemically synthesized dyes commonly used in the textiles industry today.

Also known as Phoenician purple, royal purple, imperial purple, or imperial dye, this rare dye dates back several millennia to the bronze age when the Phoenicians from Tyre, Lebanon, on the Levantine coast, produced it for the ancient Greeks, Persians, Byzantines, and the Roman empire to clad emperors and kings with luxury textiles. Tyrian purple was once worth more than its weight in gold for its prized deep rich purple. In 301 CE, during the Roman Empire, one pound of Tyrian purple dye was priced at approximately three Troy pounds of gold, roughly $66,000 in today’s currency.

Current producers extract and harvest Tyrian purple from the murex shellfish in much the same way as the ancient Phoenicians. Thousands — approximately 10,000 or (54 kilograms (119 lb.) of these predatory sea snails are required to make diminishing quantities of Tyrian purple to produce 1 gram of the dye, making it impracticable, expensive, and environmentally unfriendly. Ancient dye producers all but drove the murex species to extinction along the coasts of Phoenicia, evident in the vast deposits of the shells excavated on the outskirts of Sidon, Tyre, and across the Mediterranean.

Conagen’s Tyrian purple, produced by precision fermentation and bioconversion, is a natural, sustainable dye ideal for textile companies under pressure to deliver fashions more sustainably and with a reduced global environmental footprint, especially from manufacturing.

“Conagen is democratizing the exclusive use of a color once reserved for royalty — now obtainable on a global scale,” said Casey Lippmeier, Ph.D., senior vice president of innovation. “Our fermentation and bioconversion technologies enable us to offer true-to-nature products. By leveraging Conagen’s bioengineering and commercial manufacturing capabilities, we’re unlocking Tyrian purple’s great potential as an accessible and sustainable dye. We expect Tyrian purple to inspire fresh ideas in multiple industries, making this rare and exciting color more marketable with planet-conscious consumers.”

The Tyrian purple technology is based on two of Conagen’s many key bioengineering platforms, which enable accelerated product development timelines for its competitive phenolics, terpenoids, proteins, and peptide molecules.

As an example, Conagen’s phenolics platform was used to make an important antioxidant, hydroxytyrosol, the active health ingredient found in oil, juice, and fruit in olives. Using another platform, Conagen has optimized the production of different amino acid-based products, including the nutraceutical antioxidant ergothioneine, a “longevity vitamin” currently branded as “Ergoactive” by Conagen’s pipeline partner Blue California. To produce the Tyrian purple, Conagen drew from both proprietary platforms to develop novel enzymes which increase the conversion efficiency of precursors to the dye.

“Conagen has further solidified its leadership in the bioeconomy by rapidly producing multiple novel and interesting molecules, such as Tyrian purple,” said Lippmeier. “Our technology platforms have been meticulously engineered and improved upon for over a decade, and they are extremely efficient at making targeted compounds from an expanding array of molecular classes for our internal product development and collaborative ventures.”

Conagen aims to replace petroleum-based ingredients and reduce carbon footprints with green technologies. Tyrian purple adds to Conagen’s natural color offerings, including several carotenoids made by fermentation which have been scaled to global production. As a dye, Tyrian purple is ideal for textile fabrics, clothing, handbags, and related accessories.

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About Conagen

Conagen is making the impossible possible. Our scientists and engineers use modern synthetic biology tools to program micro-organisms and enzymes on a molecular level to produce high-quality, sustainable, natural products manufactured worldwide via precision fermentation and bioconversion. We focus on the bioproduction of high-value ingredients for food, nutrition, flavors and fragrances, pharmaceuticals, and renewable materials.

Attachments



Ana Arakelian, Head of Public Relations and Communications
Conagen
+1-781-271-1588
ana.arakelian@conagen.com

SOURCE : Conagen

BC PLATFORMS SELECTED TO DELIVER KEY SINGAPORE POPULATION HEALTH STUDY

KUALA LUMPUR, Jan 9 (Bernama) — BC Platforms (BCP), a global leader in healthcare data management and analytics, has been selected to analyse and manage data collected from the Health for Life in Singapore (HELIOS) study, which forms part of the SG100K data set for Singapore’s National Precision Medicine programme.

The HELIOS study is a state-of-the-art population cohort study established and led by the Lee Kong Chian School of Medicine (LKCMedicine) at Nanyang Technological University, Singapore (NTU Singapore).

According to BCP in a statement, the population study aims to identify environmental, lifestyle and genetic factors that cause heart disease, diabetes, cancer, and other chronic diseases in Singapore.

“I’m delighted that we have more good news coming out of Singapore, a major focus for deploying our clinical solutions and driving precision medicine, where we are working with leading Asian healthcare institutions.

“This latest partnership should make it easier for health service providers to determine optimal patients treatment pathways in major diseases areas, based on population health insights using our genomic data management platform,” said its deputy managing director, Nino da Silva.

As part of Singapore’s SG100K study, the HELIOS study will recruit up to 50,000 men and women, aged 30-84 years old, from the Singapore population progressively over the next two years.

BCP will be providing BC|INSIGHT and BC|RQUEST for management of LKCMedicine’s genotype and phenotype patient data from a large Asian cohort in a safe and secure manner.

The project will benefit from BCP’s latest software solution, the ‘Trusted Collaboration Environment’ and the recently upgraded to its acclaimed BC|INSIGHT open platform version 7.

The platform has a high focus on user experience, it is fully equipped with cohort building tools and capabilities to automate data release approval processes and highly dynamic open workspaces.

— BERNAMA

TESSA THERAPEUTICS UNVEILS 2023 STRATEGIC OUTLOOK, CORPORATE UPDATE

KUALA LUMPUR, Jan 4 (Bernama) — Singapore-based Tessa Therapeutics Ltd (Tessa), a clinical-stage cell therapy company developing next-generation cancer treatments for hematological malignancies and solid tumours, will prioritise the development of its allogeneic “off-the-shelf” CD30.CAR-modified Epstein-Barr virus-specific T-cell (EBVST) therapy platform this year.

At the same time, the company will seek strategic options for the development of its TT11 autologous CAR-T platform with other companies, based on its strategic outlook and corporate update for 2023.

“The decision to prioritise the allogeneic or “off-the-shelf-approach” over the autologous platform followed the progress and new data with the TT11X clinical programme.

“The data demonstrated TT11X to be well-tolerated at all dosing levels, eliciting a 79 per cent overall response rate and 43 per cent complete response rate among 14 heavily pre-treated CD30-positive Hodgkin lymphoma patients,” it said in a statement today.

The company added that these developments are the first of what is expected to be a milestone-rich year ahead as the company seeks to build the value of its pipeline to its fullest potential with available resources.

Its president and chief executive officer (CEO), Thomas Willemsen said he believed that this strategic refocus on the allogeneic platform positions the company at the forefront of CAR-T innovation for 2023 and beyond.

“This optimism is based on the compelling safety and efficacy data that continue to be generated by our TT11X programme and the potential patient benefit in treating CD30-positive lymphomas, and potentially solid tumours where there is a significant unmet medical need,” he said.

In 2022, Tessa enhanced its executive management team with the appointment of Willemsen as CEO and Wilson W. Cheung as chief financial officer.

The company also expanded its board with the addition of Amy Schulman and Darren Carroll from Polaris Partners, which led the company’s US$126 million Series A financing round.

— BERNAMA

MALAYSIA, CHINA EXPLORING THE DEVELOPMENT OF VIRTUAL POWER PLANTS

KUALA LUMPUR, Dec 30 (Bernama) — Malaysia and China seek to jointly explore the development trend of virtual power plants (VPPs) under the worldwide green and low-carbon transformation.

Towards this goal, the China-Malaysia Virtual Power Plant Project Achievements Conference and China-Malaysia Virtual Power Plant Development Cloud Forum were held online today, the Shanghai Energy Technology Development Co Ltd (SETD) said in a statement.

The subsidiary of China’s State Power Investment Corp Ltd said the event was of great significance for the two countries in terms of cooperation in the VPP business and promoting the green and low-carbon energy transformation.

“At the forum, the panelists exchanged views and gave suggestions on the development status and trend of new energy and energy storage in Malaysia, and the development potential, technical research, construction and operation and business model of the virtual power plant.

“Going forward, China and Malaysia will work together to promote green, low-carbon and smart energy transition and make new contributions to tackling climate change and achieving sustainable development for mankind,” it said.

In 2022, SETD, together with domestic and Malaysian universities and counterparts, led the preparation of a research report, “Development Potential Analysis and Cooperation Prospect of VPP in China and Malaysia”, both in English and Chinese.

The report offers an in-depth analysis of China and Malaysia’s energy and power development status and the development potential of VPPs in the two countries.

It also puts forward a preliminary design of the operation scheme of VPPs in Malaysia, as well as suggestions for bilateral cooperation in this field.

— BERNAMA

THE 18TH ICIF OPENS IN SHENZHEN TO SEEK GLOBAL CULTURAL COOPERATION

SHENZHEN, China, Dec. 30, 2022 /Xinhua-AsiaNet/–

The 18th China (Shenzhen) International Cultural Industries Fair (ICIF) kicked off on December 28, 2022. This year’s ICIF is held mainly offline, complemented by synchronized online exhibitions. It is estimated that over 2,500 governmental delegations, cultural institutions and businesses will attend the fair on site, while 800 institutes and enterprises will set up online booths.

The ICIF is the first cultural fair in China recognized by the Global Association of the Exhibition Industry (UFI). Since its inception in Shenzhen in 2004, the fair has seen a continuous increase in exhibition scale, audience, and level of internationalization. It has now grown into a key engine for China’s cultural industrial growth, as well as an important platform and window to spread Chinese culture to the world, according to Shenzhen Municipal People’s Government.

According to statistics, every year, the ICIF gathers over 100,000 exhibits from cultural and creative industries at home and abroad, and more than 4,000 cultural investment and financing projects are displayed and traded at the fair. By participating in the event, numerous excellent overseas businesses and institutions have successfully expanded their market and found new opportunities for cooperation and development.

Notably, an International Exhibition Hall has been set up on this year’s Cloud ICIF. A total of 300 overseas cultural institutions and businesses from 30 countries and regions across the globe have been invited to the online fair. Domestic and foreign cultural products and projects are being displayed on the online platform, with a strong emphasis on promoting cultural exchange and trade between China and other countries along the Belt and Road, and expanding the international network for cultural trade.

Miao Song, founder and director of the Canada China Art-Tech (CCAT), brought along its Canadian partners Telefilm Canada, Concordia University, and The 7 Fingers. She said, “This is the 4th time we have participated in the ICIF. This year we see more participating countries and more diverse exhibits. Particularly, the technology culture products have never failed to impress me.”

In response to a question on why the CCAT takes part in the fair, Director Song believes that the CCAT shares many core values with the ICIF in supporting the growth of China’s cultural industry and assisting Chinese cultural products in reaching a global audience. She added: “The CCAT exhibits are diversified, embracing science and technology, arts, academia and humanities, and other sectors, so it fits well with the ICIF’s high-quality, diverse and comprehensive display mode.” 

Additionally, this fair has opened up new avenues for attracting foreign investment and exhibitors, so as to engage more domestic and international cultural institutions and businesses, and help exhibitors accelerate their integration into China’s “dual circulation” development pattern and develop new markets. It will build itself into a significant cultural platform for international procurement, investment promotion, people-to-people exchange, and open cooperation. A total of 10,931 buyers from 108 countries and regions, like France, Germany, and Pakistan, have registered for the online fair.

Ambassador JUDYTH NSABABERA from Consulate General of the Republic of Uganda in Guangzhou said: “This year, we are honored to participate in the 18th ICIF online and offline. We hope that through this exchange, we can show our African culture, products and projects on such an excellent platform as the ICIF, and we also hope that through this ICIF we can help the development of cultural industries in China and Uganda reach a higher level.”

As a state-level, international and comprehensive fair for cultural industries, the ICIF has celebrated 17 sessions so far. It has promoted the development of cultural industry across the country as well as that of Shenzhen City. The fair has become a signature event to showcase Shenzhen’s achievements in economic, social and cultural development and an important window into this growing metropolis. Currently, the added value of Shenzhen’s cultural industries has exceeded 25 million yuan, accounting for over 8% of the city’s GDP.

Director Song Miao said, “Shenzhen is an international city with high inclusiveness and a front-runner in opening up. Boasting a large number of high-tech enterprises and a huge market, it has maintained a robust growth momentum in foreign investment and continuously witnessed an increase in the number and scale of businesses going global. The CCAT wants to further cooperate with Shenzhen businesses and institutions in film-making, film-related activities, technology development, and project venture capital investment to achieve win-win results. In addition, we would like to express our sincere thanks to and our full confidence in the ICIF’s positive role in boosting the cooperation.”

Source: Shenzhen Municipal People’s Government

–BERNAMA